HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 54385335, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Tri-o-tolylphosphine | HCID 80271 | — |
| Reactant | 2-(5-Bromothiophen-2-Yl)-1,3-Dioxolane | HCID 12269970 | — |
| Reactant | HCID 178479072 | HCID 178479072 | — |
| Catalyst | palladium(II) acetate | HCID 167845 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 54385335 | HCID 54385335 | — |
Reaction Steps
7-[3-[5-(1,3-dioxolan-2-yl)thien-2-yl)-2-propenyl]hexahydro-1H-azepin-2-imine, monohydrochloride ##STR199## 198 A) The Isomer B title material of Example 18 in acetonitrile is coupled to 2-(5-bromo-2-thienyl)dioxolane in the presence palladium acetate, tri-o-tolylphosphine, and triethylamine by the method of Example 32 to provide 7-[3-[5-(1,3-dioxolan-2-yl)thien-2-yl]-2-propenyl]hexahydro-1H-azepin-2-one as primarily the E isomer.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05883251 |
| Source dataset | uspto-grants-1999_03 |
| ORD ID | ord-3afc342fefcd4e0cb2b0dfd1204c2b38 |
| Source note | uspto-grants-1999_03 |