Boc-L-Valine → HCID 86753920, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure in Example 3A except using N-[(1,1-dimethylethoxy)carbonyl]-L-valine and (±)-7-(1-hydroxypropyl)-8-methylindolizino[1,2-b]quinolin-9(11H)-one. 1H NMR (CDCl3) d 8.34 (s, 1H), 8.22 (m, 1H), 7.91 (d, J=8.2 Hz, 1H), 7.80 (m, 1H), 7.62 (m, 1H), 7.34 (two s, 1H), 5.94 (m, 1H), 5.26 (s, 2H), 5.04 (two br d, J=9.3 Hz, 1H), 4.36 (two d, J=4.5 Hz, 1H), 2.36 (s, 3H), 2.4-2.2 (m, 1H), 2.1-1.8 (m, 2H), 1.44 and 1.38 (two s, 9H), 1.00 (overlapping t and d, 9H).

Provenance & Evidence