反应详情

The product of stage (i) (32.6 g) was added to a stirred suspension of stannous chloride dihydrate (133 g) in ethanol (300 ml). After refluxing for 2 hours the solution was poured into ice-water (2500 ml) and extracted with ethyl acetate (3×500 ml). The combined extracts were washed with saturated sodium chloride solution, dried and evaporated to give 24.3 g of the desired product as a brown solid, mp 82°-84° C.

1. temperatureAfter refluxing for 2 hours the solution
2. extractionextracted with ethyl acetate (3×500 ml)
3. washThe combined extracts were washed with saturated sodium chloride solution
4. customdried
5. customevaporated