Sodium Hydroxide → HCID 6918145, compound

HRID 1418824Notes

Reaction equation

HRID 1418824 reaction equation
[CH3:1][N:2]([CH2:4][CH2:5][C:6]([P:12](=[O:15])([OH:14])[OH:13])([P:8](=[O:11])([OH:10])[OH:9])[OH:7])[CH3:3].[OH-].[Na+:17]>>[Na+:17].[CH3:1][N:2]([CH2:4][CH2:5][C:6]([P:8](=[O:9])([OH:11])[O-:10])([P:12](=[O:13])([OH:14])[OH:15])[OH:7])[CH3:3]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 198716Olpadronic acid

Product 1

HCID 6918145HCID 6918145, compound

Procedure

Add with constant stirring 11,11 kg of (II) to 33.3 l sodium hydroxide (50,7 g/l). Filter if necessary, add 122 l of methanol and dry in an oven with forced air circulation until constant weight. 10.7 kg of (III) is obtained.

Workup

  1. additionAdd
  2. filtrationFilter if necessary,
  3. additionadd 122 l of methanol
  4. customdry in an oven with forced air circulation until constant weight

Sources & evidence

ORD record
ord-d44b86c1f7ae4e49bcbcaff6158f0ca5
Source dataset
uspto-grants-1999_03
Patent number
US05885973

Reaction notes

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