N-benzyl-3-nitrobenzamide → 3-amino-N-benzylbenzamide

Participants

Reaction Steps

A sample of the product of step (a), 8.8 g, was dissolved in 100 ml of methanol and hydrogenated with 0.4 g of 10% palladium on carbon and 50 PSI hydrogen. After 90 minutes, the mix was filtered and evaporated. The solid residue was slurried in ethyl ether, and filtered to provide crude N-phenylmethyl-3-aminobenzamide, mp 95°-100° C., m.s. (M+H)+ =227

Provenance & Evidence