Dimethylformamide → HCID 9884526, compound

Participants

Reaction Steps

To a mixture of 9.2 g of diethanolamine, 200 ml of N,N-dimethylformamide, and 15 g of anhydrous potassium carbonate was added 20 g of 2-amino-4-chloro-6-(2,5-dichlorophenyl)-1,3,5-triazine with stirring at room temperature and the mixture was further stirred at room temperature for 7 hours. This reaction mixture was diluted with 2L (liters) of water with stirring and then stirred for 1 hour. The resulting crystal crop was harvested by filtration, rinsed with water, and dried to obtain 24 g of white crystals. Those crystals were recrystallized from methanol, collected by filtration, and dried to provide 21 g of the title compound as white crystals. m.p. 199°-200° C.

Provenance & Evidence