HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Cyano-1-[3-(N-t-butoxycarbonylpiperid-4-yl)indol-5-yl]-1H-benzimidazole → 5-Cyano-1-[3(piperid-4-yl)indol-5-yl]-1H-benzimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Cyano-1-[3-(N-t-butoxycarbonylpiperid-4-yl)indol-5-yl]-1H-benzimidazole | HCID 70069291 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 5-Cyano-1-[3(piperid-4-yl)indol-5-yl]-1H-benzimidazole | HCID 44317196 | 64% |
Reaction Steps
5-Cyano-1-[3-(N-t-butoxycarbonylpiperid-4-yl)indol-5-yl]-1H-benzimidazole was used, and methylene chloride was used as solvent. Filtration afforded the title compound (64%) as a yellow solid: IR (KBr) 2229 cm-1 ; 13C NMR (CD3OD) δ 137.4, 129.6, 126.6, 124.7, 123.6, 120.6, 119.2, 117.9, 117.5, 116.4, 114.8, 112.8, 109.9, 44.6, 31.3, 29.4. Anal. calcd. for C21H19N5.3 HCl.1.25 H2O: C, 53.29; H, 5.22; N, 14.80. Found: C, 53.63; H, 5.34; N, 14.68.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05886008 |
| Source dataset | uspto-grants-1999_03 |
| ORD ID | ord-2f7a76b4bda8444c8d4f6d906d4beaf6 |
| Source note | uspto-grants-1999_03 |