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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1419204Generated: October 26, 2026

Pyruvic Acid → Creatine pyruvate monohydrate

https://huagongshe.com/reaction/1419204

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyruvic AcidHCID 1060—
ReactantIsopropanolHCID 3776—
ReactantCreatine MonohydrateHCID 80116—
SolventWaterHCID 962—
ProductCreatine pyruvate monohydrateHCID 9881182—

Reaction Steps

One mole of creatine monohydrate with a molecular weight of 149.15 g/mole is mixed with one mole of pyruvic acid having a molecular weight of 88.06 g/mole. To this mixture is added 20 gms of a 1:1 v/v mixture of isopropyl alcohol and water. The powder and liquid are stirred together while being held at or below 60° C. by a cooling bath at that temperature until the mixture solidifies. The resultant powder is dried to yield crystalline creatine pyruvate monohydrate. This product has a molecular weight of 237.21 and decomposes at 112°-114° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05886040
Source datasetuspto-grants-1999_03
ORD IDord-1f6d8f297995436ba5cbf7b74b5cbc96
Source noteuspto-grants-1999_03