HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → HCID 178478765, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | 6-Amidino-1-carbamoylmethyl-2-naphthol.hydrochloride | HCID 136454270 | — |
| Reactant | HCID 178479746 | HCID 178479746 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 178478765 | HCID 178478765 | 114.3% |
Reaction Steps
20 Milliliters of 20% hydrous pyridine was added to 1.02 g of 4-[(2-hydroxyethyl)aminoiminomethylamino]benzoic acid.hydrochloride, 1.0 g of 6-amidino-1-carbamoylmethyl-2-naphthol.hydrochloride, 884 mg of DCC and 43.6 mg of DMAP, followed by stirring for 2 hours under cooling with ice and then 24 hours at room temperature. Thereafter, the same procedure as in Example 1 was carried out to obtain 1.17 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05885990 |
| Source dataset | uspto-grants-1999_03 |
| ORD ID | ord-2b2fa6a1ceca4229a95b43291aedaf34 |
| Source note | uspto-grants-1999_03 |