Hydrochloric Acid → 6-Cyano-1-carboxy-2-naphthol

Participants

Reaction Steps

A solution prepared by dissolving 71 g of potassium hydroxide in 1.5 liter of water was added to a solution prepared by dissolving 24.0 g of 6-cyano-1-methoxycarbonyl-2-naphthol in 4.7 liters of methanol, followed by stirring at 50°-60° C. for 24 hours. After cooling, the reaction mixture was made to an acidic solution with addition of 10% hydrochloric acid. The precipitate was collected by filtration and washed with a small amount of water to obtain 14.8 g of the desired product.

Provenance & Evidence