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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 141931Generated: October 26, 2026

2-Fluoro-5-(trifluoromethyl)phenyl isocyanate → 1-(2-Fluoro-5-(trifluoromethyl)phenyl)-3-(4-(2-oxo-1,2-dihydropyrido[2,3-b]pyrazin-8-yloxy)naphthalen-1-yl)urea

https://huagongshe.com/reaction/141931

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-5-(trifluoromethyl)phenyl isocyanateHCID 2733380—
Reactant8-(4-aminonaphthalen-1-yloxy)pyrido[2,3-b]pyrazin-2(1H)-oneHCID 46901250—
Product1-(2-Fluoro-5-(trifluoromethyl)phenyl)-3-(4-(2-oxo-1,2-dihydropyrido[2,3-b]pyrazin-8-yloxy)naphthalen-1-yl)ureaHCID 44133726—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-d735167009714ff9877cbf01dc4a89e1
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)