HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminothiophenol → Benzo(d)thiazol-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminothiophenol | HCID 8713 | — |
| Reactant | Thiocyanate | HCID 9322 | — |
| Reactant | Diphenylamine | HCID 11487 | — |
| Reactant | Bromine | HCID 24408 | — |
| Product | Benzo(d)thiazol-2-amine | HCID 8706 | — |
Reaction Steps
If the desired 2-amino benzenethiol 8-scheme 3 is not commercially available it can be synthesized by reaction of the phenyl aniline with the thiocyanate anion in the presence of an oxidant(like bromine) to produce the 2-amino benzthiazole 7-scheme 3. This thiazole can then be hydrolyzed to the desired 2-amino benzenethiol 8-scheme 3 with a strong base like NaOH in a protic solvent (i.e., EtOH). ##STR11##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05886044 |
| Source dataset | uspto-grants-1999_03 |
| ORD ID | ord-80cea5848a7445389c70c8b2fa9a2534 |
| Source note | uspto-grants-1999_03 |