HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Trifluoromethoxy)phenyl Isocyanate → N-(2-Hydroxy-4-nitrophenyl)-N'-(2-trifluoromethyloxyphenyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Trifluoromethoxy)phenyl Isocyanate | HCID 608953 | — |
| Reactant | 2-Amino-5-Nitrophenol | HCID 4984721 | — |
| Product | N-(2-Hydroxy-4-nitrophenyl)-N'-(2-trifluoromethyloxyphenyl)urea | HCID 21184649 | 60% |
Reaction Steps
N-(2-Hydroxy-4-nitrophenyl)-N'-(2-trifluoromethoxyphenyl)urea was prepared from 2-hydroxy 4-nitro aniline (500 mg, 3.24 mmol) and 2-trifluoromethoxy phenyl isocyanate (3.24 mmol) according to the procedure in General Method B. The product was purified by dilution with methylene chloride and precipitation with hexanes. Filtering afforded the title compound(0.69 g, 60%). EI-MS m/z 358(M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05886044 |
| Source dataset | uspto-grants-1999_03 |
| ORD ID | ord-2dfe8ad53e884f95a30e4bf39a614946 |
| Source note | uspto-grants-1999_03 |