2-Bromophenyl isocyanate → HCID 53843945, compound

HRID 1419397Notes

Reaction equation

HRID 1419397 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[S:11]([NH:14][C:15]2[CH:21]=[CH:20][CH:19]=[CH:18][C:16]=2[NH2:17])(=[O:13])=[O:12])[CH:4]=[CH:3][CH:2]=1.[Br:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[N:29]=[C:30]=[O:31]>>[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[S:11]([NH:14][C:15]2[CH:21]=[CH:20][CH:19]=[CH:18][C:16]=2[NH:17][C:30]([NH:29][C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=2[Br:22])=[O:31])(=[O:12])=[O:13])[CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 1370972-Bromophenyl isocyanateHCID 21263225HCID 21263225, compound

Product 1

HCID 53843945HCID 53843945, compoundYield 46.2%

Procedure

The urea was synthesized from 2-((8-quinolinyl) sulfonyl amino) aniline(1 mmol) and 2-bromo phenyl isocyanate(1 mmol) by general Method B. It was purified by dilution with methylene chloride and precipitation with hexane. Filtering afforded the desired compound(0.23 g, 46%).EI-MS m/z 495(M-H)-

Workup

  1. customIt was purified by dilution with methylene chloride and precipitation with hexane
  2. filtrationFiltering

Sources & evidence

ORD record
ord-6c951ab4570f457ab2796acb592f0b99
Source dataset
uspto-grants-1999_03
Patent number
US05886044

Reaction notes

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