HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodine → 2-Propyl-3-t-butyl-4-hydroxy-5-isopropylphenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodine | HCID 807 | — |
| Reactant | 1,1,3,3-Tetramethyl-disiloxane | HCID 18659 | — |
| Reactant | 2-Propyl-3-t-butyl-5-isopropylbenzoquinone | HCID 57066423 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Propyl-3-t-butyl-4-hydroxy-5-isopropylphenol | HCID 54017886 | — |
Reaction Steps
Dissolve 2-propyl-3-t-butyl-5-isopropylbenzoquinone (10 mmol), 1,1,3,3-tetramethyldisiloxane (1.79 mL, 10 mmol) and iodine (0.05 g) in methylene chloride (30 mL). Stir at reflux for 30 minutes and extract with 1N sodium hydroxide (30 mL). Acidify the aqueous phase with concentrated hydrochloric acid and extract into ethyl acetate (4×10 mL), dry (Na2SO4) and evaporate the solvent in vacuo to give 2-propyl-3-t-butyl-4-hydroxy-5-isopropylphenol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05886156 |
| Source dataset | uspto-grants-1999_03 |
| ORD ID | ord-51b10a4762c64575a3884efa6e978758 |
| Source note | uspto-grants-1999_03 |