3-Phenoxythiophene-2-carbaldehyde → HCID 15410671, compound

HRID 1419538Notes

Reaction equation

HRID 1419538 reaction equation
[O:1]([C:8]1[CH:12]=[CH:11][S:10][C:9]=1[CH:13]=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:15][C:16]([F:30])([F:29])[C:17]1[CH:18]=[C:19]([S:23]([CH2:26][C:27]#[N:28])(=[O:25])=[O:24])[CH:20]=[CH:21][CH:22]=1>>[O:1]([C:8]1[CH:12]=[CH:11][S:10][C:9]=1/[CH:13]=[C:26](/[S:23]([C:19]1[CH:20]=[CH:21][CH:22]=[C:17]([C:16]([F:30])([F:15])[F:29])[CH:18]=1)(=[O:25])=[O:24])\[C:27]#[N:28])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Procedure

Reaction of 3-phenoxythiophen-2-carboxaldehyde and 3-trifluoromethylphenylsulfonylacetonitrile as in Example 1 gave (E)-3-(3-phenoxythien-2-yl)-2-[3-(trifluoromethyl)phenylsulfonyl]acrylonitrile

Sources & evidence

ORD record
ord-3219ce95b895449b9a802fe053badcdf
Source dataset
uspto-grants-1999_03
Patent number
US05886195

Reaction notes

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