Sodium Chloride → HCID 53982091, compound

Participants

Reaction Steps

6.48 g (12.14 mmol) of 18 and 6.31 g (20 mmol) of tetrabutylammonium fluoride (hydrate) in 150 ml of THF is stirred overnight at room temperature. Then, it is hydrolyzed with sodium chloride solution, extracted with ethyl acetate, washed with sodium chloride solution and dried on sodium sulfate. After concentration by evaporation, the residue is chromatographed on silica gel (mobile solvent: EE:H=8:2), whereby 2.41 g (8.3 mmol) of title compound 19 is obtained.

Provenance & Evidence