Triphenylphosphine → HCID 140398710, compound

Participants

Reaction Steps

A solution of allyl (E)-2-(2-thienyl)-2-[(5-benzhydryloxy-4-pyranon-2-yl methoxy)imino]acetate (from Step 1, Example 2, 2.09 gm, 4.17 mmol), in a mixture of methylene chloride and ethyl acetate (25 ml: 55 ml) was treated with sodium 2-ethylhexanoate (693 mg, 4.17 mmol), triphenylphosphine (109 mg, 0.417 mmol) and Pd (PPh3)4 (193 mg, 0.167 mmol) and the mixture was stirred at room temperature for 5 hrs. The resulting precipitate was filtered, washed with a mixture of ether-ethyl acetate (1:1) and dried in vacuo to afford a white solid (2.0 gm, 99% yield).

Provenance & Evidence