Cyclopropyl isothiocyanate → HCID 178527172, compound

HRID 1419746Notes

Reaction equation

HRID 1419746 reaction equation
Cl.[NH2:2][C:3]1[CH:7]=[C:6]([Cl:8])[S:5][C:4]=1[S:9]([NH2:12])(=[O:11])=[O:10].[CH:13]1([N:16]=[C:17]=S)[CH2:15][CH2:14]1>>[Cl:8][C:6]1[S:5][C:4]2[S:9](=[O:10])(=[O:11])[N:12]=[C:17]([NH:16][CH:13]3[CH2:15][CH2:14]3)[NH:2][C:3]=2[CH:7]=1

Participants

3

Reactant 2

HCID 92463Cyclopropyl isothiocyanateHCID 688206263-Amino-5-chlorothiophene-2-sulfonamide hydrochloride

Product 1

HCID 178527172HCID 178527172, compound

Procedure

The title compound was prepared from 3-amino-5-chlorothiophene-2-sulfonamide hydrochloride and cyclopropyl isothiocyanate by a procedure analogous to the procedure described in example 3Bc-d; mp 272°-273° C.; 1H-NMR (DMSO-d6 ): δ 0.55 (m, 2H), 0.78 (m, 2H), 2.6 (m, 1H), 7.10 (s, 1H), 7.88 (br. s, 1H), 10.95 (br. s, 1H).

Sources & evidence

ORD record
ord-33975899472a47529c6019f47f432af6
Source dataset
uspto-grants-1999_03
Patent number
US05889002

Reaction notes

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