4-Phenylbutyl isothiocyanate → HCID 178527192, compound

HRID 1419753Notes

Reaction equation

HRID 1419753 reaction equation
Cl.[NH2:2][C:3]1[CH:7]=[C:6]([Cl:8])[S:5][C:4]=1[S:9]([NH2:12])(=[O:11])=[O:10].[C:13]1([CH2:19][CH2:20][CH2:21][CH2:22][N:23]=[C:24]=S)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[Cl:8][C:6]1[S:5][C:4]2[S:9](=[O:10])(=[O:11])[N:12]=[C:24]([NH:23][CH2:22][CH2:21][CH2:20][CH2:19][C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[NH:2][C:3]=2[CH:7]=1

Participants

3

Reactant 2

HCID 1248814-Phenylbutyl isothiocyanateHCID 688206263-Amino-5-chlorothiophene-2-sulfonamide hydrochloride

Product 1

HCID 178527192HCID 178527192, compound

Procedure

The title compound was prepared from 3-amino-5-chlorothiophene-2-sulfonamide hydrochloride and 4-phenylbutyl isothiocyanate by a procedure analogous to the procedure described in example 3Bc-d; mp 201°-205° C.; 1H-NMR (DMSO-d6): δ 1.55 (m, 4H), 2.6 (t, 2H), 3.2 (q, 2H), 7.04 (s, 1H), 7.1-7.4 (m, 6H), 10.94 (br. s, 1H).

Sources & evidence

ORD record
ord-3379c4a6ee5841e1bc0eb4541aa41ad1
Source dataset
uspto-grants-1999_03
Patent number
US05889002

Reaction notes

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