L-Alaninol → HCID 178461808, compound

HRID 1419757Notes

Reaction equation

HRID 1419757 reaction equation
Cl[C:2]1[NH:7][C:6]2[CH:8]=[C:9]([Cl:11])[S:10][C:5]=2[S:4](=[O:13])(=[O:12])[N:3]=1.[NH2:14][C@H:15]([CH2:17][OH:18])[CH3:16]>O>[Cl:11][C:9]1[S:10][C:5]2[S:4](=[O:13])(=[O:12])[N:3]=[C:2]([NH:14][C@@H:15]([CH3:16])[CH2:17][OH:18])[NH:7][C:6]=2[CH:8]=1

Participants

4

Reactant 2

HCID 80307L-AlaninolHCID 118320583,6-Dichloro-4h-thieno[3,2-e][1,2,4]thiadiazine 1,1-dioxide

Product 1

HCID 178461808HCID 178461808, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The title compound was prepared from 3,6dichloro-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide and L-alaninol by a procedure analogous to the procedure described in example 1Bb; mp 204°-206° C. (water), 1H-NMR (DMSO-d6): δ 1.11 (d, 3H), 3.4 (d, 2H), 3.78 (m, 1H), 4.95 (br. s, 1H), 7.05 (br. s, 1H), 7.09 (s, 1H), 10.8 (br. s, 1H).

Sources & evidence

ORD record
ord-537fb9daab83421a82b4756829ed9bb2
Source dataset
uspto-grants-1999_03
Patent number
US05889002

Reaction notes

Loading…