1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid → HCID 15411480, compound

HRID 1419767Notes

Reaction equation

HRID 1419767 reaction equation
[CH:1]1([N:4]2[C:13]3[C:8](=[CH:9][C:10]([F:16])=[C:11](F)[C:12]=3[F:14])[C:7](=[O:17])[C:6]([C:18]([OH:20])=[O:19])=[CH:5]2)[CH2:3][CH2:2]1.[CH3:21][N:22]([CH2:24][C:25]1[N:26]=[C:27]2[CH2:32][NH:31][CH2:30][CH2:29][N:28]2[CH:33]=1)[CH3:23]>>[CH:1]1([N:4]2[C:13]3[C:8](=[CH:9][C:10]([F:16])=[C:11]([N:31]4[CH2:30][CH2:29][N:28]5[CH:33]=[C:25]([CH2:24][N:22]([CH3:23])[CH3:21])[N:26]=[C:27]5[CH2:32]4)[C:12]=3[F:14])[C:7](=[O:17])[C:6]([C:18]([OH:20])=[O:19])=[CH:5]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 5354141-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acidHCID 45099778N,N-Dimethyl-1-(5,6,7,8-tetrahydroimidazo[1,2-a]pyrazin-2-yl)methanamine

Product 1

HCID 15411480HCID 15411480, compound

Procedure

Using 1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and (2-dimethylaminomethyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine, the same procedure as in Production Example 1 was followed to yield the title compound.

Sources & evidence

ORD record
ord-d41280f3761543b987e99493c05bcfb4
Source dataset
uspto-grants-1999_03
Patent number
US05889009

Reaction notes

Loading…