Water → 4-(1-Methylethenyl)cyclohexanone

Participants

Reaction Steps

4.1 g of a 37% strength solution of HF in trimethylamine were added dropwise with stirring at room temperature to 8.0 g (0.038 mol) of 1-trimethylsilyloxy-4-isopropenyl-1-cyclohexene in 100 ml of CH2Cl2, and the mixture was subsequently stirred for 2 hours. Water was added, extraction was carried out with CH2Cl21 and the combined organic phases were dried and concentrated. 4.7 g (90% of theory) were obtained of a colorless oil which was reacted without further purification.

Provenance & Evidence