O-Toluidine → HCID 54058840, compound

Participants

Reaction Steps

3-Propanoyl-4-chloro-8-(3-methylthiopropoxy)quinoline (1.2 g, 3.71 mmol) and o-toluidine (0.795 g, 7.42 mmol) was refluxed in acetonitrile (18 ml) for 100 min. The solvent was evaporated and the residue was purified by column chromatography (methylene chloride:methanol 100:3). 1.45 g (99%) of the title compound was obtained.

Provenance & Evidence