HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Methylbenzyl)-piperidin-4-ol → N-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-2-[4-hydroxy-4-(4-methyl-benzyl)-piperidin-1-yl]-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Methylbenzyl)-piperidin-4-ol | HCID 10536242 | — |
| Reactant | N-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-2-chloro-acetamide | HCID 70046914 | — |
| Product | N-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-2-[4-hydroxy-4-(4-methyl-benzyl)-piperidin-1-yl]-acetamide | HCID 70046072 | — |
Reaction Steps
The title compound, m.p. 136°-138° C. and MS: m/e=468 (M+), was prepared from N-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-2-chloro-acetamide and 4-(4-Methyl-benzyl)-piperidin-4-ol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05889026 |
| Source dataset | uspto-grants-1999_03 |
| ORD ID | ord-78c52ebbcef44098b13aa02a6d89ccd8 |
| Source note | uspto-grants-1999_03 |