4-Benzyl-4-piperidinol → HCID 70048638, compound

HRID 1419923Notes

Reaction equation

HRID 1419923 reaction equation
[C:1]([Si:5]([CH3:20])([CH3:19])[O:6][C:7]1[CH:12]=[CH:11][C:10]([NH:13][C:14](=[O:18])[CH2:15][CH2:16]Cl)=[CH:9][CH:8]=1)([CH3:4])([CH3:3])[CH3:2].[CH2:21]([C:28]1([OH:34])[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]1)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[CH2:21]([C:28]1([OH:34])[CH2:33][CH2:32][N:31]([CH2:16][CH2:15][C:14]([NH:13][C:10]2[CH:11]=[CH:12][C:7]([O:6][Si:5]([C:1]([CH3:4])([CH3:3])[CH3:2])([CH3:20])[CH3:19])=[CH:8][CH:9]=2)=[O:18])[CH2:30][CH2:29]1)[C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1

Participants

3

Reactant 2

HCID 981524-Benzyl-4-piperidinolHCID 70046531HCID 70046531, compound

Product 1

HCID 70048638HCID 70048638, compound

Procedure

The title compound, MS: m/e=468 (M+), was prepared from N-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-3-chloro-propionamide and 4-benzyl-4-hydroxypiperidin.

Sources & evidence

ORD record
ord-416a9a52145a4cadb2099614ff301997
Source dataset
uspto-grants-1999_03
Patent number
US05889026

Reaction notes

Loading…