HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-Chloro-2-methoxybenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-Chloro-o-anisic acid | HCID 93682 | — |
| Product | 4-Chloro-2-methoxybenzoyl chloride | HCID 22142450 | — |
Reaction Steps
A solution of 2.0 g of 4-chloro-o-anisic acid in 22 ml of thionyl chloride is heated at reflux for 1 hour. The volatiles are evaporated in vacuo to give a residue which is is concentrated from toluene three times and dried under vacuum to give 2.0 g of the desired product as a residue.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05889001 |
| Source dataset | uspto-grants-1999_03 |
| ORD ID | ord-476ce9b529674d77bc39ce75e6d263d2 |
| Source note | uspto-grants-1999_03 |