HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 85711217, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 76411778 | HCID 76411778 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Anisole | HCID 7519 | — |
| Product | HCID 85711217 | HCID 85711217 | 77.4% |
Reaction Steps
The general method of Preparation 20 was followed using [S-(R*,R*)]-2-([2-[3-(1-tert-butoxycarbonyl-3-methyl-butylcarbamoyl)-pyridin-2-yldisulfanyl]-pyridine-3-carbonyl]-amino)-4-methyl-pentanoic acid tert-butyl ester (1.9 g, 2.9 mmol) in 20 mL dichloromethane, anisole (1.5 mL), and 10 mL trifluoroacetic acid. The crude product was recrystallized from methanol/water to yield 1.2 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05889034 |
| Source dataset | uspto-grants-1999_03 |
| ORD ID | ord-73a076191c3242cd93f34485202f757f |
| Source note | uspto-grants-1999_03 |