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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 142012Generated: October 25, 2026

Tetrahydrofuran → 1-(5-Bromo-4-methyl-thiophen-2-yl)-3-(3,5-dichloro-phenyl)-4,4,4-trifluoro-3-hydroxy-butan-1-one

https://huagongshe.com/reaction/142012

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactanttert-Butyl methyl etherHCID 15413—
ReactantLithium ionHCID 28486—
ReactantHydrideHCID 166653—
Reactant1-(3,5-Dichlorophenyl)-2,2,2-trifluoroethan-1-oneHCID 2758231—
Reactant1-(5-Bromo-4-methylthiophen-2-yl)ethan-1-oneHCID 45480353—
Product1-(5-Bromo-4-methyl-thiophen-2-yl)-3-(3,5-dichloro-phenyl)-4,4,4-trifluoro-3-hydroxy-butan-1-oneHCID 86658038—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-571fa6c8621d4016bd7509575eb8289b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)