HCID 178419549, compound → HCID 178511401, compound

Participants

Reaction Conditions

Reaction Steps

t-Butyl-6-(2-benzyloxy-1-iminoethylamino)2-t-butoxycarbonylamino-4,4-dioxo-4-thiahexanoate hydrobromide (0.97 g) (prepared by a method analagous to that described in Example 1A from Intermediates A and 3B) was stirred in 4M HCl/dioxane (12 ml) at room temperature for 6 hours. The solvent was evaporated and the residual gum triturated with dry ether (20 ml). A white solid slowly formed on standing. The ether was decanted off and the very hygroscopic solid washed with fresh ether and dried in vacuo with warming to 65° C.

Provenance & Evidence