HCID 53708626, compound → HCID 54428176, compound

Participants

Reaction Steps

To a solution of 2-(butyloxycarbonylamino)-6-(benzyloxycarbonylamino)-4,4-dioxo-4-thiahexanoic acid tert-butyl ester (200 mg) in methanol (5 ml) was added Pd/C (50%) (Degussa type) (200 mg) and the mixture hydrogenated at room temperature until no further change was observed. The reaction mixture was then filtered through a pad of Hyflo and the residue washed with fresh methanol (2×2 ml). The combined filtrates were evaporated to dryness to give 119 mg of the title compound as an almost colourless glass.

Provenance & Evidence