HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → ALLYL 4-BROMOBUTYRATE
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Allyl Alcohol | HCID 7858 | — |
| Reactant | 4-Bromobutyryl chloride | HCID 70225 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | ALLYL 4-BROMOBUTYRATE | HCID 7010323 | 95% |
Reaction Steps
4-Bromobutryl chloride (18.6 g) was treated with allyl alcohol (5.8 g) in the presence of pyridine (8 g) in dry dichloromethane at 0° C. for 0.5 hours. The solution was treated with aqueous HCl and warmed to room temperature. The organic layer was separated, washed with saturated aqueous brine, dried (MgSO4) and evaporated to give the title compound as a colourless oil, 19.7 g, 95% yield
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06071899 |
| Source dataset | uspto-grants-2000_06 |
| ORD ID | ord-9190722aae10416280c7065235af5f40 |
| Source note | uspto-grants-2000_06 |