Allyl Alcohol → HCID 18781991, compound

Participants

Reaction Steps

Sodium (1.15 g) was added to allyl alcohol (50 ml) and this solution treated with allyl 4-(acetylthio)butanoate (10.Og) at room temperature for 20 mins. 4-Acetoxyazetidinone (6.5 g) was added and stirring continued at 20° C. for 1 h The resulting mixture was poured into excess ethyl acetate and the layers separated. The organic layer was washed with water, brine, dried (MgSO4), filtered and evaporated. The residue was chromatographed on silica gel (diethyl ether) to give the title compound as a yellow oil, 5.5 g. 48% yield

Provenance & Evidence