1-Phenyl-1,3,8-triazaspiro(4.5)decan-4-one → HCID 18782340, compound

HRID 1420652Notes

Reaction equation

HRID 1420652 reaction equation
[Cl:1][C:2]1[CH:11]=[CH:10][C:9]([Cl:12])=[C:8]2[C:3]=1[CH2:4][CH2:5][C:6](=O)[CH2:7]2.[C:14]1([N:20]2[C:24]3([CH2:29][CH2:28][NH:27][CH2:26][CH2:25]3)[C:23](=[O:30])[NH:22][CH2:21]2)[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[ClH:1].[Cl:1][C:2]1[CH:11]=[CH:10][C:9]([Cl:12])=[C:8]2[C:3]=1[CH2:4][CH2:5][CH:6]([N:27]1[CH2:26][CH2:25][C:24]3([N:20]([C:14]4[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=4)[CH2:21][NH:22][C:23]3=[O:30])[CH2:29][CH2:28]1)[CH2:7]2

Participants

3

Reactant 2

HCID 705561-Phenyl-1,3,8-triazaspiro(4.5)decan-4-oneHCID 10775032HCID 10775032, compound

Product 1

HCID 18782340HCID 18782340, compound

Procedure

The title compound, m.p. 290-293° C. was prepared in accordance with the general method of example 1 from 5,8-dichloro-2-tetralone and 1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one.

Sources & evidence

ORD record
ord-0479b96c64344868b6eca098455b0166
Source dataset
uspto-grants-2000_06
Patent number
US06071925

Reaction notes

Loading…