Allyl bromide → HCID 18782408, compound

HRID 1420653Notes

Reaction equation

[Cl:1][C:2]1[CH:11]=[CH:10][C:9]([Cl:12])=[C:8]2[C:3]=1[CH2:4][CH2:5][CH:6]([N:13]1[CH2:29][CH2:28][C:16]3([N:20]([C:21]4[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=4)[CH2:19][NH:18][C:17]3=[O:27])[CH2:15][CH2:14]1)[CH2:7]2.[CH2:30](Br)[CH:31]=[CH2:32]>>[ClH:1].[CH2:32]([N:18]1[C:17](=[O:27])[C:16]2([CH2:28][CH2:29][N:13]([CH:6]3[CH2:5][CH2:4][C:3]4[C:8](=[C:9]([Cl:12])[CH:10]=[CH:11][C:2]=4[Cl:1])[CH2:7]3)[CH2:14][CH2:15]2)[N:20]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH2:19]1)[CH:31]=[CH2:30]

Participants

Reactant 2

HCID 7841Allyl bromide

HCID 9954388HCID 9954388, compound

Product 1

HCID 18782408HCID 18782408, compound

Procedure

The title compound, m.p.>250° C. and MS: m/e=470.4, 472.4 (M+H+) was prepared in accordance with the general method of example 4 from 8-(5,8-dichloro-1,2,3,4-tetrahydro-2-naphthyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one and allyl bromide.

Sources & evidence

ORD record: ord-c8f68315440941b492b850bed2734e5b
Source dataset: uspto-grants-2000_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06071925

Reaction notes

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