Benzoyl chloride → HCID 18782333, compound

HRID 1420657Notes

Reaction equation

Cl.[Cl:2][C:3]1[CH:12]=[CH:11][C:10]([Cl:13])=[C:9]2[C:4]=1[CH2:5][CH2:6][CH:7]([N:14]1[CH2:30][CH2:29][C:17]3([N:21]([C:22]4[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=4)[CH2:20][NH:19][C:18]3=[O:28])[CH2:16][CH2:15]1)[CH2:8]2.[C:31](Cl)(=[O:38])[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1>>[ClH:2].[C:31]([N:19]1[C:18](=[O:28])[C:17]2([CH2:29][CH2:30][N:14]([CH:7]3[CH2:6][CH2:5][C:4]4[C:9](=[C:10]([Cl:13])[CH:11]=[CH:12][C:3]=4[Cl:2])[CH2:8]3)[CH2:15][CH2:16]2)[N:21]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH2:20]1)(=[O:38])[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1

Participants

Reactant 2

HCID 7412Benzoyl chloride

HCID 18782340HCID 18782340, compound

Product 1

HCID 18782333HCID 18782333, compound

Procedure

The title compound, m.p. 220° C. dec. was prepared in accordance with the general method of example 4 from 8-(5,8-dichloro-1,2,3,4-tetrahydro-2-naphthyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one hydrochloride and benzoyl chloride.

Sources & evidence

ORD record: ord-6bee7e47a9e2414e91166dd8d8f46927
Source dataset: uspto-grants-2000_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06071925

Reaction notes

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