1-Phenyl-1,3,8-triazaspiro(4.5)decan-4-one → HCID 86755440, compound
Reaction equation
[C:1]1(=[N:10]O)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.[C:12]1([N:18]2[C:22]3([CH2:27][CH2:26]N[CH2:24][CH2:23]3)[C:21](=O)[NH:20][CH2:19]2)[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[CH:1]1([N:10]2[CH2:26][CH2:27][C:22]3([N:18]([C:12]4[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=4)[CH2:19][NH:20][CH2:21]3)[CH2:23][CH2:24]2)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1Participants
3
Procedure
The title compound, m.p.>250° C. and MS: m/e=348.4 (M+H+) was prepared in accordance with the general method of example 11 from 2,3-dihydro-1H-inden-1-one oxime and 1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one.
Sources & evidence
- ORD record
- ord-6c612eab554e4141976dbad38ec650a5
- Source dataset
- uspto-grants-2000_06
- Patent number
- US06071925
Reaction notes
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