1-Phenyl-1,3,8-triazaspiro(4.5)decan-4-one → HCID 18782377, compound
Reaction equation
[Cl:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][CH2:6][C:7]2=[N:12]O.[C:14]1([N:20]2[C:24]3([CH2:29][CH2:28]N[CH2:26][CH2:25]3)[C:23](=[O:30])[NH:22][CH2:21]2)[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[ClH:1].[Cl:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][CH2:6][CH:7]2[N:12]1[CH2:28][CH2:29][C:24]2([N:20]([C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=3)[CH2:21][NH:22][C:23]2=[O:30])[CH2:25][CH2:26]1Participants
3
Procedure
The title compound, m.p.>250° C. and MS: m/e=396.2 (M+H+) was prepared in accordance with the general method of example 11 from 5-chloro-3,4dihydro-1(2H)-naphthalenone oxime and 1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one.
Sources & evidence
- ORD record
- ord-6b474a7780d74f9d93c94204231215ac
- Source dataset
- uspto-grants-2000_06
- Patent number
- US06071925
Reaction notes
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