1-Phenyl-1,3,8-triazaspiro(4.5)decan-4-one → HCID 18782388, compound

HRID 1420660Notes

Reaction equation

HRID 1420660 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[C:7](=O)[CH2:6][CH2:5]2.[C:12]1([N:18]2[C:22]3([CH2:27][CH2:26][NH:25][CH2:24][CH2:23]3)[C:21](=[O:28])[NH:20][CH2:19]2)[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[CH:7]([N:25]1[CH2:24][CH2:23][C:22]3([N:18]([C:12]4[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=4)[CH2:19][NH:20][C:21]3=[O:28])[CH2:27][CH2:26]1)[CH2:6][CH2:5]2

Participants

3

Reactant 2

HCID 705561-Phenyl-1,3,8-triazaspiro(4.5)decan-4-oneHCID 1425995-Chloro-1-indanone

Product 1

HCID 18782388HCID 18782388, compound

Procedure

The title compound, m.p.>250° C. and MS: m/e=382.2 (M+H+) was prepared in accordance with the general method of example 34 from 5-chloro-2,3-dihydro-1H-inden-1-one and 1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one.

Sources & evidence

ORD record
ord-4298eab610f54502a7d71f2b529b77f8
Source dataset
uspto-grants-2000_06
Patent number
US06071925

Reaction notes

Loading…