1-Phenyl-1,3,8-triazaspiro(4.5)decan-4-one → HCID 18782390, compound

HRID 1420661Notes

Reaction equation

HRID 1420661 reaction equation
[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([CH2:6][CH2:7][CH2:8][C:9]2=[N:12]O)=[C:4]([F:14])[CH:3]=1.[C:15]1([N:21]2[C:25]3([CH2:30][CH2:29]N[CH2:27][CH2:26]3)[C:24](=[O:31])[NH:23][CH2:22]2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[ClH:1].[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([CH2:6][CH2:7][CH2:8][CH:9]2[N:12]2[CH2:29][CH2:30][C:25]3([N:21]([C:15]4[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=4)[CH2:22][NH:23][C:24]3=[O:31])[CH2:26][CH2:27]2)=[C:4]([F:14])[CH:3]=1

Participants

3

Reactant 2

HCID 705561-Phenyl-1,3,8-triazaspiro(4.5)decan-4-oneHCID 86755441HCID 86755441, compound

Product 1

HCID 18782390HCID 18782390, compound

Procedure

The title compound, m.p.>250° C. and MS: m/e=414.2 (M+H+) was prepared in accordance with the general method of example 11 from 7-chloro-5-fluoro-3,4-dihydro-1(2H)-naphthalenone oxime and 1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one.

Sources & evidence

ORD record
ord-c69b4d0642a2403c86e0bc4d2f604bbd
Source dataset
uspto-grants-2000_06
Patent number
US06071925

Reaction notes

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