Methyl iodide → HCID 18782430, compound

HRID 1420662Notes

Reaction equation

[ClH:1].[CH2:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH:3]1[N:11]1[CH2:27][CH2:26][C:14]2([N:18]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:17][NH:16][C:15]2=[O:25])[CH2:13][CH2:12]1.[CH3:28]I>>[ClH:1].[CH2:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH:3]1[N:11]1[CH2:12][CH2:13][C:14]2([N:18]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:17][N:16]([CH3:28])[C:15]2=[O:25])[CH2:26][CH2:27]1

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 18782387HCID 18782387, compound

Product 1

HCID 18782430HCID 18782430, compound

Procedure

The title compound, m.p.>250° C. and MS: m/e=362.2 (M+H+) was prepared in accordance with the general method of example 4 from 8-indan-2-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one hydrochloride (1:1) and methyl iodide.

Sources & evidence

ORD record: ord-3ae9611bfb424ecbb52734bce6a80dfe
Source dataset: uspto-grants-2000_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06071925

Reaction notes

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