Methyl iodide → HCID 18782419, compound

HRID 1420664Notes

Reaction equation

HRID 1420664 reaction equation
[ClH:1].[C:2]1([N:8]2[C:12]3([CH2:17][CH2:16][N:15]([CH:18]4[C:27]5[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=5)[CH2:21][CH2:20][CH2:19]4)[CH2:14][CH2:13]3)[C:11](=[O:28])[NH:10][CH2:9]2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:29]I>>[ClH:1].[CH3:29][N:10]1[C:11](=[O:28])[C:12]2([CH2:17][CH2:16][N:15]([CH:18]3[C:27]4[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=4)[CH2:21][CH2:20][CH2:19]3)[CH2:14][CH2:13]2)[N:8]([C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH2:9]1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 18782359HCID 18782359, compound

Product 1

HCID 18782419HCID 18782419, compound

Procedure

The title compound, m.p. 232-234° C. was prepared in accordance with the general method of example 4 from 1-phenyl-8-(1,2,3,4-tetrahydro-1-naphthyl)-1,3,8-triaza-spiro[4.5]decan-4-one hydrochloride (1:1) and methyl iodide.

Sources & evidence

ORD record
ord-490daf01225b4f31a3fe4502cd5db7b9
Source dataset
uspto-grants-2000_06
Patent number
US06071925

Reaction notes

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