Methyl iodide → HCID 18782355, compound

HRID 1420665Notes

Reaction equation

[ClH:1].[CH:2]1([N:11]2[CH2:27][CH2:26][C:14]3([N:18]([C:19]4[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=4)[CH2:17][NH:16][C:15]3=[O:25])[CH2:13][CH2:12]2)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3]1.[CH3:28]I>>[ClH:1].[CH:2]1([N:11]2[CH2:27][CH2:26][C:14]3([N:18]([C:19]4[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=4)[CH2:17][N:16]([CH3:28])[C:15]3=[O:25])[CH2:13][CH2:12]2)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3]1

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 18782401HCID 18782401, compound

Product 1

HCID 18782355HCID 18782355, compound

Procedure

The title compound, m.p. 200-203° C. and MS: m/e=362.2 (M+H+) was prepared in accordance with the general method of example 4 from (RS)-8-indan-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one hydrochloride (1:1) and methyl iodide.

Sources & evidence

ORD record: ord-c55bbbb1aec5417aa46e876bdb221c5c
Source dataset: uspto-grants-2000_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06071925

Reaction notes

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