1-Phenyl-1,3,8-triazaspiro(4.5)decan-4-one → HCID 18782357, compound

HRID 1420669Notes

Reaction equation

HRID 1420669 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][CH2:5][C:6]2=O.[C:12]1([N:18]2[C:22]3([CH2:27][CH2:26][NH:25][CH2:24][CH2:23]3)[C:21](=[O:28])[NH:20][CH2:19]2)[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[ClH:1].[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][CH2:5][CH:6]2[N:25]1[CH2:24][CH2:23][C:22]2([N:18]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[CH2:19][NH:20][C:21]2=[O:28])[CH2:27][CH2:26]1

Participants

3

Reactant 2

HCID 705561-Phenyl-1,3,8-triazaspiro(4.5)decan-4-oneHCID 113326814-chloro-2,3-dihydro-1H-inden-1-one

Product 1

HCID 18782357HCID 18782357, compound

Procedure

The title compound, white solid, m.p.>230° C. and MS: m/e=382.2 (M+H+) was prepared in accordance with the general method of example 34 from 4-chloro-indan-1-one and 1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one.

Sources & evidence

ORD record
ord-e175a396e1234a52bcafa664137c2441
Source dataset
uspto-grants-2000_06
Patent number
US06071925

Reaction notes

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