1-Bromo-3-chloropropane → HCID 86755446, compound

Participants

Reaction Steps

The compound was synthesized in the same manner as in example 1. Treatment of 3-ethylcarbazole (2.0 g, 0.0102 mol) with NaH (0.27 g, 0.0112 mol) succeeded by the addition of 1-bromo-3-chloropropane (1.77 g, 0.0112 mol) in DMF gave the title compound 2.3 g (82%) as a yellow oil. 1H-NMR (δ, CDCl3): 1.35 (t, 3H); 2.4 (m, 2H); 2.8 (q, 2H); 3.35 (t, 1H); 3.45 (t, 1H); 4.35 (t, 2H); 7-7.4 (m, 4H); 7.9 (s, 2H); 8.1 (d, 2H). The product was isolated as an 1:1 mixture of the 3-bromo- and 3-chloro derivatives.

Provenance & Evidence