反应详情

A solution of 0.35 mol of the compound obtained in Step 1 in 400 ml of methanol and 1.5 equivalents of sodium borohydride is stirred for 6 hours at ambient temperature and then 500 ml of acidified water are slowly added. The precipitate obtained is taken up in ether; the organic phase is subsequently extracted, dried, filtered and then evaporated off under reduced pressure, allowing the expected product to be isolated.

1. customThe precipitate obtained
2. extractionthe organic phase is subsequently extracted
3. customdried
4. filtrationfiltered
5. customevaporated off under reduced pressure
6. customto be isolated