Lithium borohydride → HCID 15542191, compound

Participants

Reaction Steps

To the ester of Step 1 (1.13 g, 3.07 mmol) in CH2Cl2 (30 mL) and Et2O 50 mL was added at 0∞C. LiBH4 (80 mg, 3.68 mmol). The reaction mixture was stirred at room temperature until completion. The reaction mixture was partitioned between 25% NH4OAc and EtOAc. The organic phase was separated, dried over Na2SO4 and evaporated. The title compound (275 mg) was obtained as a white solid after purification by flash chromatography.

Provenance & Evidence