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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1421143Generated: November 1, 2026

Ammonia → HCID 5327706, compound

https://huagongshe.com/reaction/1421143

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantHCID 21615652HCID 21615652—
SolventDimethylformamideHCID 6228—
ProductHCID 5327706HCID 5327706—

Reaction Conditions

Temperature150 °C

Reaction Steps

0.30 g of 3-(1-methyl-3-indolyl)-4-(3-methylphenyl) furan-2,5-dione was treated with 8 ml of DMF and 60 ml of 33% aqueous ammonia and heated at 150° C. for 5 hours and then allowed to cool. The formed precipitate was filtered off, washed with water and dried to give 162 mg of 3-(1-methyl-3-indolyl)-4-(3-methylphenyl)-1H-pyrrole-2,5-dione, m.p. 243° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUSRE036736
Source datasetuspto-grants-2000_06
ORD IDord-6f2f3891a0824c77bb74bf5fb073df95
Source noteuspto-grants-2000_06