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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1421158Generated: November 4, 2026

Dimethylformamide → HCID 18780224, compound

https://huagongshe.com/reaction/1421158

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantHCID 18780217HCID 18780217—
SolventAmmoniaHCID 222—
ProductHCID 18780224HCID 18780224—

Reaction Steps

A solution of 2.50 g of 3-[1-(3-azidopropyl)-3-indolyl]-4-(1-methyl-3-indolyl)furan-2,5-dione in 13 ml of DMF and 18 ml of 33% aqueous ammonia was heated to 140° C. for 4 hours. The product was filtered off from the cooled mixture to give 2.27 g of 3-[1-(3-azidopropyl)-3-indolyl]-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione, m.p. 222°-224° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUSRE036736
Source datasetuspto-grants-2000_06
ORD IDord-a3af57b381084efdaef3fa87a2b87146
Source noteuspto-grants-2000_06