HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(1-methyl-3-indolyl)-4-[1-[3-(methylsulphonyloxy)propyl]-3-indolyl]-1H-pyrrole-2,5-dione → 3-(1-methyl-3-indolyl)-4-[1-[3-(2-thiazolin-2-ylthio)propyl]-3-indolyl]-1H-pyrrole-2,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(1-methyl-3-indolyl)-4-[1-[3-(methylsulphonyloxy)propyl]-3-indolyl]-1H-pyrrole-2,5-dione | HCID 15163051 | — |
| Reactant | HCID 178527880 | HCID 178527880 | — |
| Product | 3-(1-methyl-3-indolyl)-4-[1-[3-(2-thiazolin-2-ylthio)propyl]-3-indolyl]-1H-pyrrole-2,5-dione | HCID 18780280 | 17.2% |
Reaction Steps
In an analogous manner to that described in Example 59, from 27 mg of 2-mercaptothiazoline and 100 mg of the product of Example 58, there were obtained 18 mg of 3-(1-methyl-3-indolyl)-4-[1-[3-(2-thiazolin-2-ylthio)propyl]-3-indolyl]-1H-pyrrole-2,5-dione m.p. 170°-173° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USRE036736 |
| Source dataset | uspto-grants-2000_06 |
| ORD ID | ord-02adf28685034de1a9face365a0ae991 |
| Source note | uspto-grants-2000_06 |